MERKURID AGAINST AGING OF ORGANISM

MERKURID AGAINST AGING OF ORGANISM

All of our visible human life, with all its events, achievements, thoughts and feelings, is placed between two dates: the day of birth and day of death. Nobody can correct or distort these events. The only universal human virtue to take on life or lose it manifests itself with relentless logic from age to age in these events. Apoptosis plays a central role in the process of aging. «et us see what it is and how you can affect it.

Apoptosis is a universal mechanism of cell death. It includes death (self-destruction) of cells that are incorrectly developing, potentially dangerous or unnecessary for the surrounding tissue. For example, the protection against cancer is based on apoptosis — neighbors of cancer cell kill themselves, forming a «dead zone», and only failure in the program of mass suicide leads to cancer.
In 2002 Nobel Prize in physiology was awarded for discovery of genes, whose main task is to encode proteins that trigger cell suicide (apoptosis). Cells execute order «to die» after a suspicion that something is wrong. This order goes through the chain of proteins, and the latter of them tells cell to execute, and it dies.

Benefit and harm of apoptosis
About 5% of all cells in our body die through apoptosis every day. Mainly there are weak, damaged, mutated, infected with a virus cells. And body restores their number, producing young viable cells.
If there is no order to die, cells can live for a very long time and bring harm to the body. If apoptosis is out of control, the death of cells becomes abnormal. Amplified, uncontrolled apoptosis causes massive cell death. One cell, having decided to commit suicide, can send a deadly message to its neighbors, and in result not only it, but a whole cell layer die.
It has long been observed that after irradiation most of cells die not from injuries but, as one can say, «at their own will». This phenomenon of collective cell suicide is mainly responsible for the consequences of heart attack and stroke.

Apoptosis and senescence (cell aging)
Canadian biologists neutralized two genes responsible for apoptosis in worms, which body have only 1 thousand cells. Worms" life became six times longer after that. The structure of human body is much more difficult, and apoptosis performs necessary function, removing damaged cells and cells with impaired function, so if you simply disable apoptosis, it will shorten the life.
Although apoptosis is clearly useful for a young body, it can lead to negative effects for health in later life, leading to aging.
Damages accumulate in aging cells, and apoptotic cell loss grows because of this.
Some old cells, that lost their ability to divide, become resistant (not-sensitive) to apoptosis, these old cells accumulate, and tissue lose its" former health after certain threshold.

The hypothesis of organism"s suicide
Scientists speculate about the existence of the genetic program of self-destruction, which gradually destroys the body.
It has been proved that death of, at least, some living creatures is the result of suicide program, very similar to apoptosis on the basis of implementation. The only question is whether such a program is inherent to man? But, possibly, we will launch another program by removing of this one.
Today many experts agree that aging and dying of an individual, that gave the offspring, is useful in terms of evolution. Aging leads to accelerating of the improvement of biological species, but also increases the survival rate of species as a whole. But we all want not only to improve our species, but also to live as long as possible, enjoying life and giving the joy of existence to our loved ones, without chronic diseases and age frailty.

Acceleration of apoptosis is acceleration of aging
1. Viruses - AIDS, hepatitis, influenza, herpes, Epstein-Barr virus, cytomegallovirus — accelerate apoptosis. Immune system energetically tries to compensate the loss of lymphocytes and begins to exhaust itself, that lead to its weakening and to wide dissemination of infection. In addition, viruses produce special proteins that protect infected cells from apoptosis, and body, unable to understand why these sells don"t die, begins generate large quantity of molecules that carry signal of cell death — apoptosis. These signals kill cells of the immune system — lymphocytes — and also cells of the liver, kidneys, blood vessels, brain. Thus starts extermination of body"s own cells. It should be noted that «wrong» apoptosis can be increased by a number of drugs (e. g. interferons).
2. Autoimmune diseases — rheumatoid arthritis, glomerulonephritis, hepatitis B, asthma, allergies, thyroiditis, prostatitis, myasthenia gravis — may reflect disturbances in the induction of apoptosis of lymphoid cells, which may react with their own antigens. For example, there is a violation of Fas-receptor on the cell surface of lymphocytes in systemic lupus erythematosus, which leads to activation of apoptosis.
3. Senile atrophy: decrease in the number of cells is one of the morphological manifestations of the aging process. This process is the most important in tissues formed by constant, non-dividing cells, for example, in brain and heart.
4. Diseases of the heart, blood vessels — heart attacks, strokes — are accounted for 63% of lethal cases. They rank first place by mortality. Apoptotic processes amplify in all of these diseases, i. e. death of the heart, blood vessels, brain cells increases, and it increases the risk of death.
Our researches show that Merkurid reduces apoptotic readiness of cells that protects them from death and restores balance between apoptosis, which is undoubtedly necessary to get rid of damaged or weakened cells, and developing of new viable cells.
Apoptosis is a programmed cell death that is triggered by specific signals. This specific signal is the presence of the marker CD95 on the surface of cells, as determined by laboratory methods. Merkurid allows to save the body"s cells.
For example, tests are made for granddaughter, 10 years old (number of CD95  — 2%), mother, 40 years old (CD95 — 25%) and grandmother, 70 years old (CD95  — 40%). Normal level of CD95 is 0 to 5%. As a result of Merkurid therapy, the number of CD95 became 6% (mother) and 8% (grandmother).
In other words, we have suspended unnaturally rapid pace of biological clocks at these people and, in addition to the fact that they have feel themselves better, symptoms of different diseases disappeared, and they extended their longevity for months and years.

Merkurid is for those who want to live long
Use of Merkurid gives our body a possibility to protect itself against growth of tumor cells and excesses of viruses and parasites, to reduce activity of inflammatory processes in digestive tract, bronchopulmonary and urinary system. It"s a chance for men to restore function of prostate and to increase sexual activity, as well as a side effect to extend their life for months and years, to look healthy, cheerful, full of vitality and energy.
Thus, direct relationship of apoptosis and many pathological conditions is obvious. Developing of Merkurid, which is able to regulate apoptosis, opens new possibilities in the treatment of malignant tumors, viral infections, nervous system diseases, immune deficiencies and autoimmune diseases, as well as gives an opportunity to extend longevity for years and decades.